Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094174 | 0.85 | NR1H2 (0.36) | TSHRALDH1A1NR1H2NR1H3HDAC8 | |
| SCHEMBL1315461 | 0.78 | TSHR (0.36) | TSHRACHENPC1CASP3RAB9A | |
| SCHEMBL1317648 | 0.76 | TSHR (0.38) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL1316336 | 0.76 | TSHR (0.38) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL11358166 | 0.76 | ALDH1A1 (0.41) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9179552 | 0.76 | ALDH1A1 (0.36) | TSHRALDH1A1NR1H2NR1H3 | |
| SCHEMBL2558125 | 0.76 | ALDH1A1 (0.38) | TSHRACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1314012 | 0.72 | TSHR (0.31) | TSHRACHE | |
| SCHEMBL7634333 | 0.72 | LMNA (0.46) | TSHRSMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL1315338 | 0.72 | TSHR (0.35) | TSHRACHENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147839-A | Solid coordination catalyst containing hydrocarbyloxysilane and vinylalkylsilane components; stereospecific, selective | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1992-09-15 | — | — | US | disclosed |