Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29780131 | 1.00 | BRD4 (0.38) | BRD4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL29780135 | 0.81 | PSEN1 (0.36) | BRD4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16915390 | 0.81 | PSEN1 (0.36) | BRD4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16915376 | 0.81 | ALDH1A1 (0.37) | BRD4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL29780137 | 0.81 | ALDH1A1 (0.37) | BRD4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16915393 | 0.74 | CXCR1 (0.41) | KMT2AMEN1NPC1RAB9ACYP1A2 | |
| SCHEMBL31532179 | 0.74 | CXCR1 (0.41) | KMT2AMEN1NPC1RAB9ACYP1A2 | |
| SCHEMBL31403240 | 0.74 | RAB9A (0.55) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL16915401 | 0.74 | RAB9A (0.55) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL9192280 | 0.73 | L3MBTL1 (0.47) | KMT2AMEN1NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069680-B1 | PROCESS FOR SYNTHESIS OF A 2-(5-ISOXAZOLYL)-PHENOL | FMC CORP (US) | 2026-03-25 | — | — | EP | claimed |
| US-12516045-B2 | Process for synthesis of a 2-thioalkyl pyrimidine | FMC CORPORATION (US) | 2026-01-06 | — | — | US | claimed |
| EP-3094631-B2 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2024-12-25 | — | — | EP | claimed |
| US-20230068064-A1 | PROCESS FOR SYNTHESIS OF A 2-THIOALKYL PYRIMIDINE | FMC CORPORATION | 2023-03-02 | — | — | US | claimed |
| EP-4069680-A1 | PROCESS FOR SYNTHESIS OF A 2-(5-ISOXAZOLYL)-PHENOL | FMC CORPORATION (US) | 2022-10-12 | — | — | EP | claimed |
| EP-4069679-A1 | PROCESS FOR SYNTHESIS OF A 2-THIOALKYL PYRIMIDINE | FMC CORPORATION (US) | 2022-10-12 | — | — | EP | claimed |
| CN-114761384-A | Process for the synthesis of 2-thioalkyl pyrimidines | FMC公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114746406-A | Method for synthesizing 2- (5-isoxazolyl) -phenol | FMC公司 | 2022-07-12 | — | — | CN | claimed |
| WO-2021113284-A1 | PROCESS FOR SYNTHESIS OF A 2-(5-ISOXAZOLYL)-PHENOL | FMC CORPORATION (US) | 2021-06-10 | — | — | WO | claimed |
| WO-2021113282-A1 | PROCESS FOR SYNTHESIS OF A 2-THIOALKYL PYRIMIDINE | FMC CORPORATION (US) | 2021-06-10 | — | — | WO | claimed |
| US-20200270238-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2020-08-27 | — | — | US | claimed |
| CN-111574510-A | Pyrimidinyloxybenzene derivatives as herbicides | FMC 公司 | 2020-08-25 | — | — | CN | claimed |
| CN-105916849-B | Pyrimidinyloxybenzene derivatives as herbicides | FMC公司 | 2020-07-07 | — | — | CN | claimed |
| US-10654840-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | claimed |
| US-20190084972-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2019-03-21 | — | — | US | claimed |
| EP-3094631-B1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2019-01-09 | — | — | EP | claimed |
| US-10131652-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION | 2018-11-20 | — | — | US | claimed |
| EP-3094631-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2016-11-23 | — | — | EP | claimed |
| US-20160333000-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2016-11-17 | — | — | US | claimed |
| WO-2015108779-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131652-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | BRD4 767/4885KMT2A 2552/4885MEN1 4381/4885 |
| US-10654840-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | BRD4 767/4885KMT2A 2552/4885MEN1 4381/4885 |
| US-20200270238-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | BRD4 767/4885KMT2A 2552/4885MEN1 4381/4885 |
| US-20230068064-A1 | PROCESS FOR SYNTHESIS OF A 2-THIOALKYL PYRIMIDINE | DHFR, RTF2, RRM2 | BRD4 2732/4885KMT2A 1924/4885MEN1 3673/4885 |
| US-20160333000-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | BRD4 767/4885KMT2A 2552/4885MEN1 4381/4885 |
| US-20190084972-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | BRD4 767/4885KMT2A 2552/4885MEN1 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.