Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837454 | 0.84 | MEN1 (0.46) | TEAD4ALDH1A1TDP1POLBMAPT | |
| SCHEMBL16918059 | 0.83 | S1PR1 (0.39) | SLC6A4HTR2AKCNH2SOS1SMN1; SMN2 | |
| SCHEMBL15360093 | 0.81 | HTR2A (0.44) | TEAD4ALDH1A1TDP1POLBMAPT | |
| SCHEMBL14670022 | 0.79 | LTA4H (0.50) | MEN1KMT2ASOS1 | |
| SCHEMBL257856 | 0.79 | SOS1 (0.55) | TEAD4ALDH1A1TDP1POLBMAPT | |
| SCHEMBL10285184 | 0.78 | TAAR1 (0.39) | — | |
| SCHEMBL257919 | 0.77 | TEAD4 (0.48) | TEAD4ALDH1A1TDP1POLBMAPT | |
| SCHEMBL18354768 | 0.76 | PTGS2 (0.36) | MAPTAR | |
| SCHEMBL15385004 | 0.74 | SLC6A4 (0.47) | TEAD4ALDH1A1TDP1POLBMAPT | |
| SCHEMBL18210774 | 0.73 | TEAD4 (0.48) | TEAD4ALDH1A1TDP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309260-B2 | Inhibitors of hepatitis C virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-9085587-B2 | Inhibitors of hepatitis C virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2015-07-21 | — | — | US | disclosed |