SCHEMBL169185

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6294929	0.74	PNMT (0.58)	PNMTADRA2AHTR2AHTR2CHTR2B
	SCHEMBL31163450	0.73	PNMT (0.48)	PNMTADRA2AHTR2AHTR2CHTR2B
	SCHEMBL24773896	0.73	PNMT (0.56)	PNMTADRA2AHTR2AHTR2CHTR2B
	SCHEMBL5874024	0.73	PNMT (0.56)	PNMTADRA2AHTR2AHTR2CHTR2B
	SCHEMBL31034844	0.73	PNMT (0.56)	PNMTADRA2AHTR2AHTR2CHTR2B
	SCHEMBL28043433	0.70	CYP19A1 (0.54)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL168488	0.70	KMT2A (0.41)	MAPTALDH1A1MEN1KMT2A
	SCHEMBL31034861	0.69	PNMT (0.52)	PNMTADRA2AHTR2AHTR2CHTR2B
	SCHEMBL24774365	0.69	PNMT (0.52)	PNMTADRA2AHTR2AHTR2CHTR2B
	SCHEMBL25031178	0.69	PNMT (0.52)	PNMTADRA2AHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.