SCHEMBL168488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3533607	0.88	KMT2A (0.42)	KMT2APDK2SMN1; SMN2ALDH1A1HTT
	SCHEMBL169287	0.79	NOTUM (0.42)	KMT2APDK2SMN1; SMN2ALDH1A1HTT
	SCHEMBL2129261	0.76	ITGB2 (0.42)	SMN1; SMN2ALDH1A1MAPT
	SCHEMBL16104413	0.75	RAB9A (0.42)	KMT2APDK2SMN1; SMN2ALDH1A1KDM4E
	SCHEMBL169273	0.75	PDK2 (0.41)	KMT2APDK2SMN1; SMN2KDM4ERECQL
	SCHEMBL12545679	0.72	KMT2A (0.60)	KMT2AALDH1A1KDM4EGLASLC2A1
	SCHEMBL169185	0.70	PNMT (0.50)	KMT2AALDH1A1MEN1MAPT
	SCHEMBL30020645	0.67	KMT2A (0.43)	KMT2ASMN1; SMN2ALDH1A1KDM4EGLA
	SCHEMBL23619758	0.67	KCNJ5 (0.46)	KMT2AALDH1A1MEN1
	SCHEMBL12545626	0.66	KMT2A (0.67)	KMT2ASMN1; SMN2ALDH1A1KDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.