SCHEMBL16920060

SCHEMBL16920060

Cn1c2ccc(-c3cccc4c3oc3ccccc34)cc2n2c3ccccc3nc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
PRKDC P78527 3/20 0.38
FLT3 P36888 3/20 0.36
GGPS1 O95749 1/20 0.36
KDM4E B2RXH2 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
PIK3CD O00329 1/20 0.35
PIK3CB P42338 1/20 0.35
BMX P51813 2/20 0.34
PTGES2 Q9H7Z7 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
FAAH O00519 1/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20041684 0.94 ALOX5 (0.40) ALOX5PRKDCFLT3GGPS1KDM4E
SCHEMBL20808053 0.87 ALOX5 (0.44) ALOX5PRKDCFLT3GGPS1KDM4E
SCHEMBL20808085 0.87 ALOX5 (0.44) ALOX5PRKDCFLT3GGPS1KDM4E
SCHEMBL16920084 0.85 ALOX5 (0.45) ALOX5PRKDCFLT3GGPS1KDM4E
SCHEMBL15631651 0.84 CHEK2 (0.38) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL22063196 0.82 ALOX5 (0.44) ALOX5PRKDCFLT3GGPS1KDM4E
SCHEMBL20807860 0.82 ALOX5 (0.42) ALOX5PRKDCFLT3GGPS1KDM4E
SCHEMBL20041708 0.82 NPC1 (0.34) ALOX5NPC1RAB9A
SCHEMBL22062711 0.82 ALOX5 (0.44) ALOX5PRKDCFLT3GGPS1KDM4E
SCHEMBL20807871 0.81 ALOX5 (0.41) ALOX5PRKDCFLT3GGPS1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-20210083200-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications UDC IRELAND LTD (IE) 2021-03-18 US disclosed
US-10862051-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2020-12-08 US disclosed
US-20190181355-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications UDC IRELAND LTD (IE) 2019-06-13 US disclosed
US-10243150-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2019-03-26 US disclosed
US-20180212159-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180212159-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20170244051-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications UDC IRELAND LTD (IE) 2017-08-24 US disclosed
US-20170244051-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications UDC IRELAND LTD (IE) 2017-08-24 US disclosed
EP-2872512-B1 BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2017-05-10 EP disclosed
US-9620724-B2 Benzimidazo[1,2-A]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2017-04-11 US disclosed
US-9620724-B2 Benzimidazo[1,2-A]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2017-04-11 US disclosed
US-20150207083-A1 BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-07-23 US disclosed
US-20150207083-A1 BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210083200-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications PAICS, EIF4A1, ECI1 ALOX5 4300/4885PRKDC 2583/4885FLT3 477/4885
US-20190181355-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications PAICS, EIF4A1, ECI1 ALOX5 4391/4885PRKDC 2687/4885FLT3 517/4885
US-10243150-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications PAICS, EIF4A1, ECI1 ALOX5 4391/4885PRKDC 2687/4885FLT3 517/4885
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications PAICS, EIF4A1, ECI1 ALOX5 4300/4885PRKDC 2583/4885FLT3 477/4885
US-20180212159-A1 ORGANIC ELECTROLUMINESCENT ELEMENT EML4, EPCAM, L1CAM ALOX5 3763/4885PRKDC 3714/4885FLT3 2243/4885
US-10862051-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications PAICS, EIF4A1, ECI1 ALOX5 4391/4885PRKDC 2687/4885FLT3 517/4885
US-20170244051-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications PAICS, EIF4A1, ECI1 ALOX5 4391/4885PRKDC 2687/4885FLT3 517/4885
US-20150207083-A1 BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS PAICS, EIF4A1, ECI1 ALOX5 4300/4885PRKDC 2583/4885FLT3 477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.