SCHEMBL169273

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3524858	0.90	PDK2 (0.42)	PDK2ESR1ESR2ABHD6KMT2A
	SCHEMBL169287	0.89	NOTUM (0.42)	PDK2KDM4ERECQLPOLBAXL
	SCHEMBL16104413	0.87	RAB9A (0.42)	PDK2KDM4ERECQLPOLBKMT2A
	SCHEMBL2129261	0.86	ITGB2 (0.42)	SMN1; SMN2MAPTLMNAGAA
	SCHEMBL13076550	0.84	TMPRSS2 (0.46)	ESR1ESR2KMT2ANPC1RAB9A
	SCHEMBL3435000	0.84	ESR1 (0.44)	ESR1ESR2ABHD6RECQLTYRO3
	SCHEMBL3434989	0.84	NAMPT (0.45)	ESR1ESR2KDM4ETYRO3MERTK
	SCHEMBL3433724	0.83	NPY2R (0.42)	ESR1ESR2KDM4EKMT2A
	SCHEMBL16104437	0.83	ESR1 (0.38)	ESR1ESR2ABHD6KDM4EPOLB
	SCHEMBL176110	0.80	ESR1 (0.47)	ESR1ESR2ABHD6TYRO3MERTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.