SCHEMBL169287

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2129261	0.90	ITGB2 (0.42)	SMN1; SMN2MAPTLMNAGAANAMPT
	SCHEMBL16104413	0.89	RAB9A (0.42)	KDM4ERECQLKMT2APOLBSMN1; SMN2
	SCHEMBL169273	0.89	PDK2 (0.41)	KDM4ERECQLKMT2APOLBSMN1; SMN2
	SCHEMBL3528315	0.88	NOTUM (0.43)	NOTUMKMT2ASMN1; SMN2NPC1RAB9A
	SCHEMBL3527784	0.79	CDK4 (0.44)	RECQLSMN1; SMN2NPC1RAB9ALMNA
	SCHEMBL168488	0.79	KMT2A (0.41)	KDM4ERECQLKMT2ASMN1; SMN2NPC1
	SCHEMBL3524858	0.78	PDK2 (0.42)	KMT2ASMN1; SMN2NPC1RAB9APDK2
	SCHEMBL13076550	0.73	TMPRSS2 (0.46)	KMT2ANPC1RAB9AGAAMEN1
	SCHEMBL3434989	0.73	NAMPT (0.45)	KDM4EKMT2ASMN1; SMN2NPC1RAB9A
	SCHEMBL3435000	0.72	ESR1 (0.44)	RECQLNPC1RAB9ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.