SCHEMBL16933720

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16933758	0.98	KCNH2 (0.46)	KCNH2OPRM1MMP2MMP9MMP8
	SCHEMBL16933867	0.92	KCNH2 (0.47)	KCNH2OPRM1MMP2MMP9MMP8
	SCHEMBL16934139	0.84	KCNH2 (0.50)	KCNH2OPRM1EPHX1GRIN2BSLC6A2
	SCHEMBL30657566	0.76	EPHX1 (0.55)	KCNH2OPRM1EPHX1GRIN2BSLC6A2
	SCHEMBL9221509	0.75	TSHR (0.45)	—
	SCHEMBL1665737	0.74	EPHX1 (0.48)	KCNH2OPRM1EPHX1GRIN2BSLC6A2
	SCHEMBL11615146	0.74	KCNH2 (0.49)	KCNH2OPRM1EPHX1GRIN2BSLC6A2
	SCHEMBL4679591	0.73	EPHX1 (0.52)	EPHX1SLC6A2TAAR1MAOASLC6A4
	SCHEMBL5001745	0.73	EPHX1 (0.52)	EPHX1SLC6A2TAAR1MAOASLC6A4
	SCHEMBL28918758	0.72	HRH1 (0.42)	TAAR1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.