SCHEMBL169378

SCHEMBL169378

Nc1ccc2cccnc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
LMNA P02545 3/20 0.50
KDM4E B2RXH2 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
NOS2 P35228 2/20 0.46
NCF1 P14598 2/20 0.46
BACE1 P56817 2/20 0.46
TP53 P04637 2/20 0.46
HSP90AA1 P07900 2/20 0.46
MAPT P10636 2/20 0.46
TSHR P16473 2/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GMNN O75496 1/20 0.46
MMP2 P08253 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MMP9 P14780 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29993166 1.00 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL30738240 1.00 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL5263750 0.98 ALDH1A1 (0.50) ALDH1A1LMNAKDM4EMEN1KMT2A
Biphenyl SCHEMBL29090174 0.90 LMNA (0.47) ALDH1A1LMNAKDM4EMEN1KMT2A
Pyrimidine SCHEMBL29083861 0.89 ALDH1A1 (0.43) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL27950781 0.86 ALDH1A1 (0.41) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL27606024 0.86 ALDH1A1 (0.41) ALDH1A1LMNAKDM4EMEN1KMT2A
Oxazole SCHEMBL27663218 0.84 ALDH1A1 (0.40) ALDH1A1LMNAKDM4EMEN1KMT2A
Hydrochlorthiazide SCHEMBL27663249 0.83 ALDH1A1 (0.39) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL169736 0.77 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115927544-B Method for detecting mismatch type and position of double-stranded DNA 广州大学 2025-03-14 CN claimed
CN-119183464-A Azanaphthalene functionalized polymers for gene and drug delivery 20迈德医疗私人有限公司 2024-12-24 CN claimed
CN-116617231-B Application of 2-amino naphthalene-embedded m-diazabenzene hydrobromide to enhancement of sterilization effect on gram-negative bacteria 沈阳药科大学 2024-11-15 CN claimed
CN-116890555-A High-temperature-resistant thermosensitive medical film with stable imaging and preparation process thereof 江苏普仁新材料科技有限公司 2023-10-17 CN claimed
CN-116617231-A Application of 2-amino naphthalene-embedded m-diazabenzene hydrobromide to enhancement of sterilization effect on gram-negative bacteria 沈阳药科大学 2023-08-22 CN claimed
CN-116574132-A Korormicin derivatives as antibiotics 维奥提卡生命科学股份有限公司 2023-08-11 CN claimed
CN-115927544-A Method for detecting double-stranded DNA mismatch type and position 广州大学 2023-04-07 CN claimed
CN-103582496-B There is the Heterobifunctional connection base of polyethylene glycol segment and the immune response modifier conjugate of being made by it 3M INNOVATIVE PROPERTIES CO. (US) 2016-05-11 CN claimed
CN-105399739-A Synthesis method of 1,8-Naphthyridin-2-amine SUZHOU HANDE CHUANGHONG BIOCHEMICAL TECH CO LTD 2016-03-16 CN claimed
US-20150141877-A1 LED AND SHOCKWAVE THERAPY FOR TATTOO REMOVAL INREXREM INC. (US) 2015-05-21 US claimed
US-20050226878-A1 Therapeutic combinations and methods including IRM compounds 3M INNOVATIVE PROPERTIES COMPANY 2005-10-13 US claimed
WO-2005067500-A2 ENHANCEMENT OF IMMUNE RESPONSES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-07-28 WO claimed
CN-1610550-A Pharmaceutical formulations comprising an immune response modifier 3M INNOVATIVE PROPERTIES CO (US) 2005-04-27 CN claimed
WO-2004080292-A2 METHOD OF TATTOO REMOVAL 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-09-23 WO claimed
US-20040181211-A1 Method of tattoo removal 3M INNOVATIVE PROPERTIES COMPANY 2004-09-16 US claimed
WO-2004071459-A2 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-08-26 WO claimed
US-20040162309-A1 Methods and compositions related to IRM compounds and toll-like receptor 8 3M INNOVATIVE PROPERTIES COMPANY 2004-08-19 US claimed
US-5498716-A 2-amino naphthyridine derivative, its preparation and its use RHONE-POULENC RORER S.A. (FR) 1996-03-12 US claimed
EP-0598765-B1 2-AMINONAPHTHYRIDINE DERIVATIVE, ITS PREPARATION AND USE RHONE POULENC RORER SA (FR) 1995-10-25 EP claimed
US-4031103-A BRONCHODILATOR AGENTS, 2,6-DIAMINOPYRIDINE, DIKETONE COMPOUND MERCK SHARP & DOHME (I.A.) CORPORATION (US) 1977-06-21 US claimed