Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | NCF1 | P14598 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169378 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL30738240 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5263750 | 0.98 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Biphenyl SCHEMBL29090174 | 0.90 | LMNA (0.47) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Pyrimidine SCHEMBL29083861 | 0.89 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL27950781 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL27606024 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Oxazole SCHEMBL27663218 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Hydrochlorthiazide SCHEMBL27663249 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL169736 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993595-B2 | Compounds | MISSION THERAPEUTICS LIMITED (GB) | 2024-05-28 | — | — | US | disclosed |
| US-20230052191-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2023-02-16 | — | — | US | disclosed |
| US-11472798-B2 | Compounds | MISSION THERAPEUTICS LTD (GB) | 2022-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11472798-B2 | Compounds | UCHL1, UCHL3, UCHL5 | ALDH1A1 300/4885LMNA 4091/4885KDM4E 175/4885 |
| US-11993595-B2 | Compounds | UCHL1, UCHL3, UCHL5 | ALDH1A1 300/4885LMNA 4091/4885KDM4E 175/4885 |
| US-20230052191-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | ALDH1A1 285/4885LMNA 4089/4885KDM4E 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.