SCHEMBL30738240

SCHEMBL30738240

Nc1ccc2cccnc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
LMNA P02545 3/20 0.50
KDM4E B2RXH2 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
NOS2 P35228 2/20 0.46
NCF1 P14598 2/20 0.46
BACE1 P56817 2/20 0.46
TP53 P04637 2/20 0.46
HSP90AA1 P07900 2/20 0.46
MAPT P10636 2/20 0.46
TSHR P16473 2/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GMNN O75496 1/20 0.46
MMP2 P08253 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MMP9 P14780 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169378 1.00 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL29993166 1.00 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL5263750 0.98 ALDH1A1 (0.50) ALDH1A1LMNAKDM4EMEN1KMT2A
Biphenyl SCHEMBL29090174 0.90 LMNA (0.47) ALDH1A1LMNAKDM4EMEN1KMT2A
Pyrimidine SCHEMBL29083861 0.89 ALDH1A1 (0.43) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL27950781 0.86 ALDH1A1 (0.41) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL27606024 0.86 ALDH1A1 (0.41) ALDH1A1LMNAKDM4EMEN1KMT2A
Oxazole SCHEMBL27663218 0.84 ALDH1A1 (0.40) ALDH1A1LMNAKDM4EMEN1KMT2A
Hydrochlorthiazide SCHEMBL27663249 0.83 ALDH1A1 (0.39) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL169736 0.77 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621222-B 6-6 Fused bicyclic heteroaryl compounds and their use as LATS inhibitors 诺华股份有限公司 2024-12-17 CN disclosed
CN-118498092-A Oiling agent for aramid fiber and application thereof 东华大学 2024-08-16 CN disclosed
CN-117551267-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 武汉柔显科技股份有限公司 2024-04-19 CN disclosed
CN-117551267-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 武汉柔显科技股份有限公司 2024-02-13 CN disclosed