Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15780579 | 0.90 | CTSB (0.40) | CTSBCTSS | |
| SCHEMBL16938907 | 0.88 | FAP (0.32) | CTSBHDAC4HDAC1FAPHDAC6 | |
| SCHEMBL16938890 | 0.88 | FAP (0.32) | CTSBHDAC4HDAC1FAPHDAC6 | |
| SCHEMBL13946717 | 0.87 | CTSB (0.40) | CTSBCTSS | |
| SCHEMBL16938974 | 0.86 | FAP (0.34) | HDAC4HDAC1FAPHDAC6 | |
| SCHEMBL12820546 | 0.86 | CTSB (0.40) | CTSBCTSS | |
| SCHEMBL11976283 | 0.85 | CTSB (0.41) | CTSBCTSSHDAC4HDAC1 | |
| SCHEMBL11976284 | 0.85 | CTSB (0.42) | CTSBCTSSHDAC4HDAC1 | |
| SCHEMBL13082504 | 0.85 | CTSB (0.42) | CTSBCTSSHDAC4HDAC1 | |
| SCHEMBL13340505 | 0.85 | FAP (0.33) | HDAC4HDAC1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364310-B1 | 4-AMINO-4-OXOBUTANOYL PEPTIDE CYCLIC ANALOGUES, INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS INC (US) | 2015-07-29 | — | — | EP | disclosed |