Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16938907 | 1.00 | FAP (0.32) | FAPTSHRHDAC4HDAC1GAA | |
| SCHEMBL16938974 | 0.90 | FAP (0.34) | FAPTSHRHDAC4HDAC1HDAC6 | |
| SCHEMBL13340505 | 0.88 | FAP (0.33) | FAPTSHRHDAC4HDAC1 | |
| SCHEMBL16938889 | 0.88 | CTSB (0.40) | FAPHDAC4HDAC1CTSBHDAC6 | |
| SCHEMBL13340502 | 0.88 | FAP (0.32) | FAP | |
| SCHEMBL16938902 | 0.87 | HDAC4 (0.32) | FAPTSHRHDAC4HDAC1 | |
| SCHEMBL16938975 | 0.85 | FAP (0.35) | FAPTSHRHDAC4HDAC1GAA | |
| SCHEMBL16938953 | 0.83 | GAA (0.33) | FAPTSHRHDAC4HDAC1GAA | |
| SCHEMBL16639051 | 0.79 | — | — | |
| SCHEMBL16938909 | 0.79 | HDAC4 (0.36) | FAPTSHRHDAC4HDAC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364310-B1 | 4-AMINO-4-OXOBUTANOYL PEPTIDE CYCLIC ANALOGUES, INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS INC (US) | 2015-07-29 | — | — | EP | disclosed |