Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL2236217 | 1.00 | CA12 (0.62) | CA12CA1CA2CA3CA4 | |
| SCHEMBL42109 | 0.97 | CA12 (0.65) | CA12CA1CA2CA3CA4 | |
| SCHEMBL30968896 | 0.97 | CA12 (0.65) | CA12CA1CA2CA3CA4 | |
| SCHEMBL1694611 | 0.97 | CA12 (0.65) | CA12CA1CA2CA3CA4 | |
| SCHEMBL42110 | 0.97 | CA12 (0.65) | CA12CA1CA2CA3CA4 | |
| Toluene SCHEMBL15670046 | 0.92 | CA12 (0.59) | CA12CA1CA2CA3CA4 | |
| Hydrochloric Acid SCHEMBL3458139 | 0.89 | CA1 (0.59) | CA12CA1CA2CA3CA4 | |
| Hydrochloric Acid SCHEMBL3458138 | 0.89 | CA1 (0.59) | CA12CA1CA2CA3CA4 | |
| SCHEMBL2518744 | 0.87 | CA12 (0.53) | CA12CA1CA2CA3CA4 | |
| SCHEMBL13015859 | 0.84 | PKM (0.55) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8907132-B2 | Process for preparing (R)-2-acetamido-N-benzyl-3-methoxy-propionamide | MSN LABORATORIES PRIVATE LIMITED (IN) | 2014-12-09 | — | — | US | disclosed |
| US-20130317109-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | CAMBREX KARLSKOGA AB (SE) | 2013-11-28 | — | — | US | disclosed |
| EP-2643293-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | Cambrex Karlskoga AB (SE) | 2013-10-02 | — | — | EP | disclosed |
| EP-2582833-A1 | ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE | Medichem, S.A. (ES) | 2013-04-24 | — | — | EP | disclosed |
| US-20130095535-A1 | ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE | MEDICHEM, S.A. (ES) | 2013-04-18 | — | — | US | disclosed |
| US-20130041180-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2013-02-14 | — | — | US | disclosed |
| EP-2534127-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN Laboratories Limited (IN) | 2012-12-19 | — | — | EP | disclosed |
| WO-2012069855-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | CAMBREX KARLSKOGA AB (SE) | 2012-05-31 | — | — | WO | disclosed |
| WO-2011158194-A1 | ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE | MEDICHEM, S.A. (ES) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011099033-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130317109-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | NAAA, APEH, DNPEP | CA12 283/4885CA1 128/4885CA2 118/4885 |
| US-20130041180-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | AMY1A, PTMA, NAAA | CA12 3088/4885CA1 1930/4885CA2 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.