SCHEMBL42109

SCHEMBL42109

COC[C@@H](N)C(=O)NCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA3 P07451 1/20 0.65
CA4 P22748 1/20 0.65
CA6 P23280 1/20 0.65
CA5A P35218 1/20 0.65
CA7 P43166 1/20 0.65
CACNA1C Q13936 1/20 0.65
SCN9A Q15858 1/20 0.65
CA9 Q16790 1/20 0.65
CA13 Q8N1Q1 1/20 0.65
CA14 Q9ULX7 1/20 0.65
CA5B Q9Y2D0 1/20 0.65
KMT2A Q03164 2/20 0.51
CARM1 Q86X55 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
PKM P14618 1/20 0.49
MAPT P10636 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1694611 1.00 CA12 (0.65) CA12CA1CA2CA3CA4
SCHEMBL42110 1.00 CA12 (0.65) CA12CA1CA2CA3CA4
SCHEMBL30968896 1.00 CA12 (0.65) CA12CA1CA2CA3CA4
Oxalic Acid SCHEMBL1694196 0.97 CA12 (0.62) CA12CA1CA2CA3CA4
Oxalic Acid SCHEMBL2236217 0.97 CA12 (0.62) CA12CA1CA2CA3CA4
Toluene SCHEMBL15670046 0.94 CA12 (0.59) CA12CA1CA2CA3CA4
Hydrochloric Acid SCHEMBL3458139 0.91 CA1 (0.59) CA12CA1CA2CA3CA4
Hydrochloric Acid SCHEMBL3458138 0.91 CA1 (0.59) CA12CA1CA2CA3CA4
SCHEMBL2518744 0.90 CA12 (0.53) CA12CA1CA2CA3CA4
SCHEMBL13015859 0.86 PKM (0.55) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3375771-B1 METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF UBE CORP (JP) 2025-11-26 EP claimed
CN-119335094-A Reversed-phase liquid chromatography method for detecting lacosamide dry syrup related substances 海南卫康制药(潜山)有限公司 2025-01-21 CN claimed
CN-118056817-A Industrial synthesis method of GS6207 key intermediate 苏州匠化生物科技有限公司 2024-05-21 CN claimed
CN-115108933-B Synthesis method of lacosamide 上药康丽(常州)药业有限公司 2023-09-29 CN claimed
CN-115108933-A Synthetic method of lacosamide 上药康丽(常州)药业有限公司 2022-09-27 CN claimed
CN-114685317-A Preparation method of medicine for treating epilepsy 成都硕德药业有限公司 2022-07-01 CN claimed
CN-113816869-A Preparation method of lacosamide process impurities 河北广祥制药有限公司 2021-12-21 CN claimed
US-10414720-B2 Process for the preparation of lacosamide UNICHEM LABORATORIES LTD. (IN) 2019-09-17 US claimed
CN-106866453-B A kind of method that microreactor prepares scheme for lacosamide 齐鲁天和惠世制药有限公司 2019-03-22 CN claimed
CN-106866453-A A kind of method that microreactor prepares scheme for lacosamide 齐鲁天和惠世制药有限公司 2017-06-20 CN claimed
EP-2399901-A1 Intermediate for producing lacosamide and a process for its preparation and conversion to lacosamide Archimica GmbH (DE) 2011-12-28 EP claimed
WO-2011158194-A1 ENZYMATIC RESOLUTION OF RACEMIC (2R,S)-2-(ACETYLAMINO)-3-METHOXY-N-(PHENYLMETHYL)PROPANAMIDE MEDICHEM, S.A. (ES) 2011-12-22 WO claimed
WO-2011099033-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN LABORATORIES LIMITED (IN) 2011-08-18 WO claimed
US-20110130350-A1 SYNTHESIS SCHEME FOR LACOSAMIDE UCB PHARMA GMBH (DE) 2011-06-02 US claimed
US-7884134-B2 From 2-(N-protected amino)-3-methoxypropionic acid; improved enantiomeric purity; O-methylation of serine derivatives UCB PHARMA GMBH (DE) 2011-02-08 US claimed
EP-1799635-B1 IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE SANOL ARZNEI SCHWARZ GMBH (DE) 2010-02-17 EP claimed
US-20080027137-A1 Synthesis Scheme for Lacosamide SCHWARZ PHARMA AG (DE) 2008-01-31 US claimed
EP-1799635-A1 IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE SCHWARZ PHARMA AG (DE) 2007-06-27 EP claimed
WO-2006037574-A1 IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE SCHWARZ PHARMA AG (DE) 2006-04-13 WO claimed
EP-1642889-A1 Improved synthesis scheme for lacosamide SCHWARZ PHARMA AG (DE) 2006-04-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027137-A1 Synthesis Scheme for Lacosamide RIMKLA, GNMT, NAAA CA12 66/4885CA1 58/4885CA2 76/4885
US-10414720-B2 Process for the preparation of lacosamide DNPEP, MGMT, NAAA CA12 68/4885CA1 45/4885CA2 328/4885
US-20110130350-A1 SYNTHESIS SCHEME FOR LACOSAMIDE RIMKLA, GNMT, MYT1 CA12 101/4885CA1 56/4885CA2 81/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.