Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19519103 | 0.86 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRMAPTDGKA | |
| SCHEMBL11330333 | 0.82 | ALDH1A1 (0.42) | LMNAALDH1A1TSHRADRA2AADRA1A | |
| SCHEMBL27900140 | 0.81 | ADRA2A (0.35) | ALDH1A1ADRA2AADRA1AMAPTBLM | |
| SCHEMBL16944240 | 0.81 | ALDH1A1 (0.40) | LMNAALDH1A1TSHRMAPTMGLL | |
| SCHEMBL2137245 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRADRA2AADRA1A | |
| SCHEMBL515043 | 0.79 | TSHR (0.47) | LMNAALDH1A1TSHRADRA2AADRA1A | |
| SCHEMBL5500580 | 0.78 | DGKA (0.48) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL24214077 | 0.76 | ADRA2A (0.40) | ADRA2AADRA1AMAPTBLMDGKA | |
| SCHEMBL1075549 | 0.76 | TSHR (0.50) | LMNAALDH1A1TSHRADRA2AADRA1A | |
| SCHEMBL8340130 | 0.76 | DGKA (0.47) | LMNAALDH1A1ADRA2AADRA1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820864-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2023-11-21 | — | — | US | disclosed |
| US-11161936-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2021-11-02 | — | — | US | disclosed |
| US-10610598-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2020-04-07 | — | — | US | disclosed |
| US-20200087454-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2020-03-19 | — | — | US | disclosed |
| US-10308763-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180134843-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
| US-20180134843-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | UNIV VANDERBILT (US) | 2018-05-10 | — | — | US | disclosed |
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | UNIV VANDERBILT (US) | 2018-05-10 | — | — | US | disclosed |
| US-9757463-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |
| US-9757463-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |
| US-9745419-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2017-08-29 | — | — | US | disclosed |
| US-9745419-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160206743-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | VANDERBILT UNIVERSITY | 2016-07-21 | — | — | US | disclosed |
| US-9161983-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2015-10-20 | — | — | US | disclosed |
| US-20150210805-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | STT3A, STT3B, B3GAT3 | LMNA 854/4885ALDH1A1 4091/4885TSHR 2588/4885 |
| US-10610598-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | STT3A, STT3B, B3GAT3 | LMNA 854/4885ALDH1A1 4091/4885TSHR 2588/4885 |
| US-20160206743-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | STT3A, STT3B, B3GAT3 | LMNA 854/4885ALDH1A1 4091/4885TSHR 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.