SCHEMBL169498

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4063741	0.77	HTR6 (0.48)	ALDH1A1CYP1A2CYP2C9HPGDMAPT
	SCHEMBL13490562	0.74	HTR2A (0.47)	ADRA2ACHRM2CHRM3ADRA2B
	SCHEMBL13490567	0.74	CCR1 (0.48)	ADRA2ACHRM2CHRM3ADRA2B
	SCHEMBL3156019	0.74	MAPT (0.52)	ALDH1A1CYP1A2CYP2C9HPGDMAPT
	SCHEMBL171474	0.72	P4HA1 (0.54)	ALDH1A1CYP1A2CYP2C9HPGDMAPT
	SCHEMBL29814719	0.71	HTR2A (0.37)	ADRA2APNMTCHRM2CHRM3ADRA2B
	SCHEMBL169373	0.71	HTR2A (0.50)	ADRA2ACHRM2CHRM3ADRA2B
	SCHEMBL13490583	0.70	CHRM2 (0.43)	ADRA2ACHRM2CHRM3ADRA2BKMT2A
	SCHEMBL8974165	0.69	NPC1 (0.53)	ALDH1A1CYP1A2MAPTADRA2ALMNA
	SCHEMBL14544148	0.69	WNT3A (0.40)	ALDH1A1MAPTCHRM2CHRM3CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.