Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955760 | 0.82 | GABRA1 (0.35) | GABRA1GABRB2SIRT2APOBEC3GPDCD1 | |
| SCHEMBL16953361 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2 | |
| SCHEMBL595285 | 0.79 | GABRA1 (0.55) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL16958191 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2 | |
| SCHEMBL16961225 | 0.75 | SIRT2 (0.36) | SIRT2APOBEC3GPDCD1CD274 | |
| SCHEMBL16960710 | 0.75 | PNMT (0.34) | SIRT2APOBEC3GPDCD1CD274 | |
| SCHEMBL16952801 | 0.75 | PDCD1 (0.50) | GABRA1GABRB2SIRT2APOBEC3GPDCD1 | |
| SCHEMBL16957607 | 0.73 | HSD11B1 (0.39) | — | |
| SCHEMBL608328 | 0.73 | GABRA1 (0.42) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL16960334 | 0.72 | PDCD1 (0.35) | GABRA1GABRB2SIRT2APOBEC3GPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |