Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122970 | 0.90 | GABRA1 (0.46) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL16953362 | 0.88 | GABRA1 (0.77) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL608328 | 0.87 | GABRA1 (0.42) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL12665692 | 0.85 | HSPA5 (0.48) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL16958194 | 0.84 | GABRA1 (0.52) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL31035446 | 0.83 | ALDH1A1 (0.40) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL16956748 | 0.83 | GABRA1 (0.39) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL31145066 | 0.83 | GPR84 (0.42) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL596529 | 0.83 | GABRA1 (0.44) | GABRA1GABRB2APOBEC3GPDCD1CD274 | |
| SCHEMBL5929950 | 0.83 | ALDH1A1 (0.40) | GABRA1GABRB2APOBEC3GPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028482-A1 | Substitution at the Central Position of Heptamethine Dyes By Aryllithium Addition for Improved Fluorophores | UNIV ARKANSAS (US) | 2026-01-29 | — | — | US | disclosed |
| US-20240358728-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, LLC (US) | 2024-10-31 | — | — | US | disclosed |
| US-20230008130-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | US | disclosed |
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |
| US-20210000847-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | US | disclosed |
| WO-2020186504-A1 | A NEW TYPE OF ANTITUMOR COMPOUNDS: DERIVATIVES OF 7-PROPANAMIDE SUBSTITUTED BENZOXABOROLE | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2020-09-24 | — | — | WO | disclosed |
| US-20200179418-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | US | disclosed |
| US-20200046745-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2020-02-13 | — | — | US | disclosed |
| US-20190282594-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2019-09-19 | — | — | US | disclosed |
| WO-2019153324-A1 | DERIVATIVES OF 7-FATTY ACID SUBSTITUTED BENZOXABOROLE AND THEIR PREPARATION AND USE | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2019-08-15 | — | — | WO | disclosed |
| US-20050080278-A1 | Production methods of citalopram and intermediates therefor | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2005-04-14 | — | — | US | disclosed |
| EP-1095926-B1 | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS CO LTD (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-20040044232-A1 | Production methods of citalopram and intermediates therefor | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| US-20020151728-A1 | Production methods of 5-phthalancarbonitrile compound and an intermediate therefor | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-10-17 | — | — | US | disclosed |
| US-6433195-B1 | 4-HALO-M-XYLYLENE GLYCOLS, ESTERS, ETHERS, AND TRIALKYLSILYL DERIVATEVES AS NOVEL INTERMEDIATES FOR CITALOPRAM PRODUCTION | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-08-13 | — | — | US | disclosed |
| US-6395910-B2 | USEFUL AS CHEMICAL INTERMEDIATE FOR CITALOPRAM WHICH IS AN ANTIDEPRESSANT; POLLUTION CONTROL | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| US-20020045770-A1 | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2002-04-18 | — | — | US | disclosed |
| US-20010056194-A1 | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-12-27 | — | — | US | disclosed |
| US-6310222-B1 | 1-(P-FLUOROPHENYL)-5-(HYDROXYMETHYL)DIHYDROBENZOFURAN | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1095926-A2 | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080278-A1 | Production methods of citalopram and intermediates therefor | TPH1, SLC6A4, CYP4F11 | GABRA1 536/4885GABRB2 553/4885APOBEC3G 1828/4885 |
| US-20230008130-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | GABRA1 1337/4885GABRB2 268/4885APOBEC3G 4630/4885 |
| US-20200046745-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | GABRA1 1337/4885GABRB2 268/4885APOBEC3G 4630/4885 |
| US-20200179418-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | GABRA1 1337/4885GABRB2 268/4885APOBEC3G 4630/4885 |
| US-20240358728-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | GABRA1 1337/4885GABRB2 268/4885APOBEC3G 4630/4885 |
| US-20010056194-A1 | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate | SLC39A11, CYP4F11, SLC39A14 | GABRA1 1411/4885GABRB2 2086/4885APOBEC3G 3966/4885 |
| US-20020045770-A1 | Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate | SLC39A11, CYP4F11, SLC39A14 | GABRA1 1411/4885GABRB2 2086/4885APOBEC3G 3966/4885 |
| US-20020151728-A1 | Production methods of 5-phthalancarbonitrile compound and an intermediate therefor | SLC39A11, CYP4F11, SLC39A14 | GABRA1 1646/4885GABRB2 2349/4885APOBEC3G 4057/4885 |
| US-20190282594-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | GABRA1 1337/4885GABRB2 268/4885APOBEC3G 4630/4885 |
| US-20210000847-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | GABRA1 1337/4885GABRB2 268/4885APOBEC3G 4630/4885 |
| US-20040044232-A1 | Production methods of citalopram and intermediates therefor | PPIF, SLC39A11, CYP4F11 | GABRA1 788/4885GABRB2 977/4885APOBEC3G 3530/4885 |
| US-20260028482-A1 | Substitution at the Central Position of Heptamethine Dyes By Aryllithium Addition for Improved Fluorophores | KCNK5, KCNA7, KCNA4 | GABRA1 1607/4885GABRB2 1007/4885APOBEC3G 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.