Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951131 | 0.88 | GRIN2B (0.38) | GRIN2BMEN1KMT2AMAPTKDM4E | |
| SCHEMBL16950764 | 0.87 | GRIN2B (0.40) | GRIN2BSMN1; SMN2ALDH1A1TSHRKCNK3 | |
| SCHEMBL16954501 | 0.84 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL16957013 | 0.83 | KCNK3 (0.43) | GRIN2BKCNK3KCNK9HCRTR1HCRTR2 | |
| SCHEMBL95873 | 0.82 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1L3MBTL1TSHRMEN1 | |
| SCHEMBL16961972 | 0.81 | CHRM2 (0.36) | L3MBTL1TSHRNPSR1HCRTR1HCRTR2 | |
| SCHEMBL16955014 | 0.79 | SCN8A (0.40) | SMN1; SMN2ALDH1A1TSHRKCNK3KMT2A | |
| SCHEMBL16955333 | 0.79 | GABRA1 (0.45) | MEN1KMT2AMAPTPDCD1CD274 | |
| SCHEMBL16953547 | 0.78 | HCRTR1 (0.40) | GRIN2BALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL24436839 | 0.77 | TP53 (0.53) | SMN1; SMN2ALDH1A1L3MBTL1TSHRKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |