Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957348 | 0.84 | P2RX1 (0.42) | TSHRTDP1GPR35P2RX1AR | |
| SCHEMBL4332289 | 0.83 | TSHR (0.58) | TSHRTDP1GPR35P2RX1AR | |
| SCHEMBL16956062 | 0.83 | TSHR (0.41) | TSHRTDP1GPR35P2RX1AR | |
| SCHEMBL1727153 | 0.82 | TSHR (0.45) | TSHRTDP1GPR35P2RX1AR | |
| SCHEMBL16951731 | 0.77 | TSHR (0.50) | TSHRTDP1GPR35ALDH1A1SMN1; SMN2 | |
| SCHEMBL11375306 | 0.77 | GPR35 (0.56) | TSHRTDP1GPR35P2RX1AR | |
| SCHEMBL10338398 | 0.77 | TSHR (0.58) | TSHRTDP1GPR35ARALDH1A1 | |
| SCHEMBL16952972 | 0.76 | TSHR (0.43) | TSHRTDP1GPR35P2RX1ALDH1A1 | |
| SCHEMBL16950684 | 0.75 | TSHR (0.71) | TSHRTDP1GPR35ALDH1A1SMN1; SMN2 | |
| SCHEMBL9694041 | 0.75 | TDP1 (0.47) | TSHRTDP1GPR35ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |