Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DNA2 | P51530 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727153 | 0.85 | TSHR (0.45) | TSHRMAPTLMNAHTTAKR1B1 | |
| SCHEMBL16951102 | 0.83 | TSHR (0.46) | TSHRMAPTLMNAHTTTDP1 | |
| SCHEMBL28481844 | 0.80 | ALDH1A1 (0.52) | TSHRMAPTALDH1A1KDM4ECASP6 | |
| SCHEMBL30196014 | 0.79 | AKR1B1 (0.45) | TSHRMAPTLMNAHTTAKR1B1 | |
| SCHEMBL23581862 | 0.79 | AKR1B1 (0.45) | TSHRMAPTLMNAHTTAKR1B1 | |
| SCHEMBL16957348 | 0.78 | P2RX1 (0.42) | TSHRMAPTLMNAHTTTDP1 | |
| Trifluoroacetic Acid SCHEMBL17873979 | 0.78 | TSHR (0.56) | TSHRMAPTLMNAHTTAKR1B1 | |
| SCHEMBL30792124 | 0.78 | AKR1B1 (0.44) | TSHRMAPTLMNAHTTAKR1B1 | |
| SCHEMBL29190134 | 0.78 | AKR1B1 (0.44) | TSHRMAPTLMNAHTTAKR1B1 | |
| SCHEMBL11375306 | 0.77 | GPR35 (0.56) | TSHRTDP1P2RX1ALDH1A1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053474-B | Flexible diamine monomer, preparation method thereof and application thereof in preparation of polyimide | 吉林大学 | 2020-03-31 | — | — | CN | claimed |
| CN-109053474-A | A kind of flexibility diamine monomer and preparation method thereof and preparing the application in polyimides | 吉林大学 | 2018-12-21 | — | — | CN | claimed |
| CN-109053474-B | Flexible diamine monomer, preparation method thereof and application thereof in preparation of polyimide | 吉林大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-109053474-A | A kind of flexibility diamine monomer and preparation method thereof and preparing the application in polyimides | 吉林大学 | 2018-12-21 | — | — | CN | disclosed |
| WO-2009071519-A9 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |