Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956762 | 0.84 | IDO1 (0.38) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL18145704 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL16951888 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL16958137 | 0.80 | MAPT (0.40) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL16957792 | 0.79 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16959583 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL16954082 | 0.79 | TSHR (0.41) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL16960789 | 0.77 | ACHE (0.56) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL14345864 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL16952358 | 0.76 | PDE4B (0.39) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |