Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951942 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL31006009 | 0.81 | DRD1 (0.42) | MAPTALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL16793397 | 0.81 | DRD1 (0.42) | MAPTALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL16952820 | 0.81 | MAPT (0.38) | MAPTALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL16959583 | 0.80 | ALDH1A1 (0.43) | MAPTALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL16951223 | 0.80 | ALDH1A1 (0.48) | MAPTALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL16954082 | 0.80 | TSHR (0.41) | MAPTALDH1A1HTTPOLBL3MBTL1 | |
| SCHEMBL16957792 | 0.77 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL16952358 | 0.77 | PDE4B (0.39) | PDE4B | |
| SCHEMBL16955823 | 0.77 | NFE2L2 (0.47) | HTTLMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |