Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 16/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 16/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10199570 | 0.86 | AKR1C3 (0.38) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL16962143 | 0.83 | AKR1C3 (0.35) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL16962848 | 0.82 | AKR1C3 (0.39) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL16959034 | 0.77 | ALOX15 (0.36) | AKR1C3AKR1C2 | |
| SCHEMBL16957528 | 0.77 | AKR1C3 (0.38) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL16959739 | 0.77 | SHBG (0.35) | AKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL16960228 | 0.76 | RXRA (0.46) | PDE3BPDE3A | |
| SCHEMBL16958297 | 0.76 | PDE2A (0.35) | — | |
| SCHEMBL16955438 | 0.75 | AKR1C3 (0.34) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL16959210 | 0.75 | NOTUM (0.37) | AKR1C3AKR1C2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |