Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104689 | 0.85 | NOTUM (0.39) | NOTUMADRB2MAPTHTTMEN1 | |
| SCHEMBL28797544 | 0.83 | P2RX7 (0.40) | NOTUMADRB2MAPTHTTMEN1 | |
| SCHEMBL27932073 | 0.81 | MAPT (0.39) | NOTUMADRB2MAPTHTTMEN1 | |
| SCHEMBL16961809 | 0.80 | NOTUM (0.36) | NOTUMADRB2MAPTHTTMEN1 | |
| SCHEMBL16957528 | 0.79 | AKR1C3 (0.38) | NOTUMLMNAAKR1C3AKR1C2TAS2R14 | |
| SCHEMBL16955438 | 0.78 | AKR1C3 (0.34) | AKR1C3AKR1C2 | |
| SCHEMBL16951994 | 0.78 | AKR1C3 (0.44) | NOTUMLMNAAKR1C3AKR1C2 | |
| SCHEMBL16952207 | 0.78 | NOTUM (0.41) | NOTUMAKR1C3AKR1C2PDE3BPDE3A | |
| SCHEMBL16950326 | 0.77 | ADRB2 (0.40) | NOTUMADRB2MAPTHTTMEN1 | |
| SCHEMBL29009770 | 0.76 | AKR1C3 (0.59) | MAPTMEN1KMT2ALMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |