Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175120 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1MEN1KMT2ATP53L3MBTL1 | |
| SCHEMBL16957050 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ATP53L3MBTL1 | |
| SCHEMBL16955362 | 0.84 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ATP53L3MBTL1 | |
| SCHEMBL11643043 | 0.81 | ESR1 (0.41) | TRPA1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL11561286 | 0.80 | MEN1 (0.36) | TRPA1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL16953670 | 0.76 | TRPA1 (0.41) | TRPA1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL16952249 | 0.75 | TRPA1 (0.44) | TRPA1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL10687771 | 0.75 | TRPA1 (0.44) | TRPA1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL16953577 | 0.74 | TSHR (0.44) | ALDH1A1MEN1KMT2AL3MBTL1HPGD | |
| SCHEMBL16959632 | 0.74 | CES2 (0.46) | ATMALDH1A1KMT2AHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |