SCHEMBL16959632

SCHEMBL16959632

C=CC[C](C)c1cccc(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46
BCHE P06276 1/20 0.46
HPGD P15428 2/20 0.37
KAT6A Q92794 2/20 0.32
ALB P02768 1/20 0.32
ERN1 O75460 1/20 0.32
KMT2A Q03164 1/20 0.31
BDKRB1 P46663 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.30
RAB9A P51151 1/20 0.30
CYP3A4 P08684 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16955362 0.84 ALDH1A1 (0.35) HPGDKAT6AKMT2AGAAALDH1A1
SCHEMBL16957491 0.79 CES2 (0.54) CES2CES1BCHEHPGDKAT6A
SCHEMBL16954240 0.77 CES2 (0.52) CES2CES1BCHEHPGDKAT6A
SCHEMBL16951954 0.77 CES2 (0.52) CES2CES1BCHEHPGDKAT6A
SCHEMBL16956836 0.76 CES2 (0.50) CES2CES1BCHEHPGDKAT6A
SCHEMBL16954427 0.76 CES2 (0.50) CES2CES1BCHEHPGDKAT6A
SCHEMBL16954788 0.76 CES2 (0.50) CES2CES1BCHEHPGDKAT6A
SCHEMBL16961928 0.74 CES2 (0.48) CES2CES1BCHEHPGDKAT6A
SCHEMBL16951985 0.74 TRPA1 (0.39) HPGDKMT2AGAAALDH1A1RAB9A
SCHEMBL16960198 0.73 CES2 (0.47) CES2CES1BCHEHPGDKAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed