Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327036 | 0.83 | CYP1A2 (0.40) | IRAK4EIF4EMKNK1MKNK2XDH | |
| SCHEMBL16954818 | 0.83 | ALK (0.39) | IRAK4EIF4EMKNK1MKNK2XDH | |
| SCHEMBL16952358 | 0.83 | PDE4B (0.39) | AR | |
| SCHEMBL16955355 | 0.83 | AR (0.47) | ARALDH1A1 | |
| SCHEMBL16958687 | 0.79 | TRPV4 (0.49) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16956762 | 0.77 | IDO1 (0.38) | IRAK4ARALDH1A1LMNAPOLB | |
| SCHEMBL10088433 | 0.77 | AR (0.44) | IRAK4EIF4EMKNK1MKNK2XDH | |
| SCHEMBL21079169 | 0.77 | XDH (0.49) | XDHALDH1A1 | |
| SCHEMBL16952110 | 0.77 | SLC6A9 (0.44) | IRAK4EIF4EMKNK1MKNK2XDH | |
| SCHEMBL524718 | 0.76 | SLC6A9 (0.45) | IRAK4EIF4EMKNK1MKNK2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |