Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860681 | 0.82 | TSHR (0.48) | TSHRALDH1A1KDM4EUSP2CYP11B2 | |
| SCHEMBL2639309 | 0.78 | MAOB (0.42) | ALDH1A1KDM4EUSP2RXFP1HPGD | |
| SCHEMBL4824074 | 0.76 | TRPV4 (0.31) | TSHR | |
| SCHEMBL30509593 | 0.76 | TSHR (0.52) | TSHRALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL101714 | 0.76 | TSHR (0.52) | TSHRALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL1003188 | 0.74 | TSHR (0.50) | TSHRALDH1A1CYP11B2ARCYP2A6 | |
| SCHEMBL16952812 | 0.74 | TSHR (0.45) | TSHRALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL61459 | 0.73 | ALDH1A1 (0.57) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22861605 | 0.73 | TRPV4 (0.52) | TSHRALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL559552 | 0.73 | TRPV4 (0.43) | CYP11B2ABCG2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |