Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30509593 | 1.00 | TSHR (0.52) | TSHRGRM5ALDH1A1CYP2A6TDP1 | |
| SCHEMBL19608728 | 0.82 | AR (0.56) | TSHRALDH1A1CYP2A6ARHPGD | |
| SCHEMBL1003862 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1CYP2A6ARPKM | |
| SCHEMBL30361887 | 0.80 | TSHR (0.52) | TSHRALDH1A1CYP2A6TDP1AR | |
| SCHEMBL3478696 | 0.80 | GRM2 (0.48) | TSHRALDH1A1CYP2A6ARPKM | |
| SCHEMBL277588 | 0.80 | TSHR (0.52) | TSHRALDH1A1CYP2A6TDP1AR | |
| SCHEMBL1003188 | 0.78 | TSHR (0.50) | TSHRALDH1A1CYP2A6ARFFAR1 | |
| SCHEMBL20468109 | 0.76 | TAAR1 (0.47) | TSHRARPKMFFAR1P2RX3 | |
| SCHEMBL1853181 | 0.76 | TRPA1 (0.52) | TSHRALDH1A1CYP2A6TDP1AR | |
| SCHEMBL253758 | 0.76 | TRPV4 (0.43) | TSHRALDH1A1CYP2A6ARPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872849-B | Method for preparing 2, 5-dimethylbenzene acetic acid | 阜新睿光氟化学有限公司 | 2025-03-18 | — | — | CN | claimed |
| US-20220242847-A1 | PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS | MERCK SHARP & DOHME CORP. (US) | 2022-08-04 | — | — | US | claimed |
| US-20220064147-A1 | PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS | MERCK SHARP & DOHME CORP. (US) | 2022-03-03 | — | — | US | claimed |
| EP-2121927-B1 | A SEQUENCE OF DSRNA: ATN-RNA, INTERVENTION USING IRNAI, USE OF A SEQUENCE OF DSRNA: ATN-RNA, A METHOD OF TREATING AND INHIBITING A BRAIN TUMOR, A KIT FOR INHIBITING CANCER CELL WHICH EXPRESSES TENASCIN, A METHOD FOR A KIT PREPARATION IN A BRAIN TUMOR THERAPY | INST CHEMII BIOORG PAN (PL) | 2012-10-10 | — | — | EP | claimed |
| CN-119866352-A | Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device | 日本化药株式会社 | 2025-04-22 | — | — | CN | disclosed |
| CN-117529509-B | Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device | 三菱瓦斯化学株式会社 | 2025-01-10 | — | — | CN | disclosed |
| CN-117355545-B | Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device | 三菱瓦斯化学株式会社 | 2024-10-18 | — | — | CN | disclosed |
| CN-114787120-B | Compound and method for producing same, resin composition, resin sheet, multilayer printed wiring board, and semiconductor device | 三菱瓦斯化学株式会社 | 2024-08-09 | — | — | CN | disclosed |
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20240217953-A1 | BICYCLIC SUBSTITUTED AROMATIC CARBOXYLIC ACID COMPOUNDS | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20240218004-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-07-04 | — | — | US | disclosed |
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| EP-0107116-A1 | Dicyanobenzenes | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-02 | — | — | EP | disclosed |
| EP-0008532-B1 | SYNTHESIS OF AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-07-20 | — | — | EP | disclosed |
| US-4298748-A | Preparation of 2-imidazolines | BASF AKTIENGESELLSCHAFT (DE) | 1981-11-03 | — | — | US | disclosed |
| US-4284769-A | FORMATION/C-C/, OXIDATON | AKZONA INCORPORATED (US) | 1981-08-18 | — | — | US | disclosed |
| US-4197388-A | TRIAZINE CATALYST | AKZONA INCORPORATED (US) | 1980-04-08 | — | — | US | disclosed |
| EP-0008532-A1 | Synthesis of amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-05 | — | — | EP | disclosed |
| US-4124763-A | A,A'-DIARYL-A,A'-BIS(DISUBSTITUTED-TRIAZINYL)-SUCCINONITRILES | AKZONA INCORPORATED (US) | 1978-11-07 | — | — | US | disclosed |
| US-3931276-A | 2-Chloro-trichloro-benzonitriles | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064147-A1 | PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS | TYMP, PNP, CD4 | TSHR 4499/4885GRM5 1736/4885ALDH1A1 2371/4885 |
| US-20220242847-A1 | PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS | PRUNE1, G6PD, ACIN1 | TSHR 4614/4885GRM5 1563/4885ALDH1A1 1817/4885 |
| US-20240217953-A1 | BICYCLIC SUBSTITUTED AROMATIC CARBOXYLIC ACID COMPOUNDS | C9, CFB, C5 | TSHR 1638/4885GRM5 4553/4885ALDH1A1 1678/4885 |
| US-20240218004-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, CCND2 | TSHR 1707/4885GRM5 3656/4885ALDH1A1 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.