SCHEMBL4824074

SCHEMBL4824074

[CH2]c1ccc([CH2])c(C#N)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TRPV4 Q9HBA0 2/20 0.31
▸ TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2639309 0.82 MAOB (0.42) TRPV4
SCHEMBL1311361 0.78 IMPDH2 (0.41) TSHR
SCHEMBL16962760 0.76 GRM4 (0.36) —
SCHEMBL1313221 0.76 CYP2A6 (0.44) TRPV4
SCHEMBL7535749 0.76 VCAM1 (0.48) TRPV4
SCHEMBL310301 0.76 TRPV4 (0.38) TRPV4
SCHEMBL1311628 0.76 MAOB (0.41) —
SCHEMBL559552 0.76 TRPV4 (0.43) TRPV4
SCHEMBL16952397 0.76 TSHR (0.48) TSHR
SCHEMBL10445051 0.76 ALDH1A1 (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7455106-B2 Polymer protective coated polymeric components for oilfield applications SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2008-11-25 — — US claimed
US-6083557-A MAKING INFRARED DETECTORS FOR INTEGRATED CIRCUITS RAYTHEON COMPANY (US) 2000-07-04 — — US claimed
US-6080987-A Infrared-sensitive conductive-polymer coating RAYTHEON COMPANY (US) 2000-06-27 — — US claimed
EP-0302457-B1 CONTAINERS HAVING A LOW PERMEABILITY TO HYDROCARBON VAPOURS, AND PROCESS FOR PRODUCING THEM SYREMONT S.p.A. (IT) 1993-08-11 — — EP claimed
EP-0271901-B1 PROCESS FOR CONSOLIDATING DISCONTINUOUS-STRUCTURED MATERIALS SYREMONT S.p.A. (IT) 1993-03-17 — — EP claimed
US-5028359-A Process of consolidating low-melting materials AUSIMONT S.R.L. (IT) 1991-07-02 — — US claimed
US-5024879-A Process for consolidating discontinuous-structured materials AUSIMONT S.P.A. (IT) 1991-06-18 — — US claimed
US-4925712-A Containers having low permeability to hydrocarbon vapors and process of producing same AUSIMONT S.P.A. (IT) 1990-05-15 — — US claimed
EP-0312025-A1 Process of consolidating low-melting materials SYREMONT S.p.A. (IT) 1989-04-19 — — EP claimed
EP-0271901-A2 Process for consolidating discontinuous-structured materials SYREMONT S.p.A. (IT) 1988-06-22 — — EP claimed
US-6083557-A MAKING INFRARED DETECTORS FOR INTEGRATED CIRCUITS RAYTHEON COMPANY (US) 2000-07-04 — — US disclosed
US-6080987-A Infrared-sensitive conductive-polymer coating RAYTHEON COMPANY (US) 2000-06-27 — — US disclosed
EP-0302457-B1 CONTAINERS HAVING A LOW PERMEABILITY TO HYDROCARBON VAPOURS, AND PROCESS FOR PRODUCING THEM SYREMONT S.p.A. (IT) 1993-08-11 — — EP disclosed
EP-0271901-B1 PROCESS FOR CONSOLIDATING DISCONTINUOUS-STRUCTURED MATERIALS SYREMONT S.p.A. (IT) 1993-03-17 — — EP disclosed
US-5028359-A Process of consolidating low-melting materials AUSIMONT S.R.L. (IT) 1991-07-02 — — US disclosed
US-4123308-A LOW TEMPERATURE PLASMA, OXIDATION UNION CARBIDE CORPORATION (US) 1978-10-31 — — US disclosed
US-3947371-A Developer material with poly(p-xylylene) coated carrier XEROX CORPORATION (US) 1976-03-30 — — US disclosed
US-3945823-A Electrostatographic reversal development with developer comprising poly(p-xylene)-coated carrier particles XEROX CORPORATION (US) 1976-03-23 — — US disclosed
US-3940530-A P-XYLYLENE POLYMER UNION CARBIDE CORPORATION (US) 1976-02-24 — — US disclosed
US-3936531-A Masking process with thermal destruction of edges of mask UNION CARBIDE CORPORATION (US) 1976-02-03 — — US disclosed
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