Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959089 | 0.91 | LMNA (0.44) | ALOX5KDM4ELMNATP53MAPT | |
| SCHEMBL16961111 | 0.87 | THRB (0.43) | ALOX5KDM4ELMNATP53MAPT | |
| SCHEMBL16954673 | 0.84 | LMNA (0.46) | ALOX5KDM4ELMNATP53MAPT | |
| SCHEMBL16955430 | 0.81 | PTGS2 (0.57) | MAPTCYP3A4PTGS2GPR84MAPK1 | |
| SCHEMBL462587 | 0.81 | ALOX5 (0.57) | ALOX5CYP3A4CYP4F2CYP4A11THRB | |
| SCHEMBL16958560 | 0.80 | CNR1 (0.41) | ALOX5KDM4EMAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL16952426 | 0.80 | CYP4F2 (0.59) | ALOX5KDM4ELMNATP53MAPT | |
| SCHEMBL16958515 | 0.80 | CNR1 (0.43) | ALOX5LMNAMEN1CYP3A4KMT2A | |
| SCHEMBL16953130 | 0.79 | ALOX5 (0.46) | ALOX5KDM4ELMNATP53MAPT | |
| SCHEMBL16957595 | 0.79 | HPGD (0.50) | CYP3A4THRBPTGS2GPR84CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |