SCHEMBL1695282

SCHEMBL1695282

CN1C(C)(C)CC(C(CCCOC(=O)C(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)O)C2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.36
GAA P10253 4/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 4/20 0.32
KDM4E B2RXH2 3/20 0.32
MAPT P10636 1/20 0.32
KCNH2 Q12809 2/20 0.32
MAOB P27338 2/20 0.31
MAOA P21397 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1695280 0.96 HMGCR (0.37) HMGCRGAAPKMHTTMEN1
SCHEMBL6359443 0.84 GAA (0.34) HMGCRGAAPKMHTTMEN1
SCHEMBL29612236 0.83 GAA (0.34) HMGCRGAAPKMHTTMEN1
SCHEMBL7759198 0.80 GAA (0.37) HMGCRGAAPKMHTTMEN1
SCHEMBL19118382 0.80 HMGCR (0.35) HMGCRGAAPKMHTTMEN1
SCHEMBL28473326 0.79 GAA (0.36) HMGCRGAAPKMHTTMEN1
SCHEMBL207800 0.79 ALDH1A1 (0.36) HMGCRGAAPKMHTTMEN1
SCHEMBL314423 0.78 HIF1A (0.43) HMGCRGAAPKMHTTMEN1
SCHEMBL2687904 0.78 GAA (0.40) HMGCRGAAPKMHTTMEN1
SCHEMBL4830860 0.76 HMGCR (0.47) HMGCRGAAPKMHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8501846-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2013-08-06 US claimed
US-20130145962-A1 Stabilizer Compositions Containing Substituted Chroman Compounds and Methods of Use CYTEC TECHNOLOGY CORP. (US) 2013-06-13 US claimed
US-20120146257-A1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECHNOLOGY CORP. (US) 2012-06-14 US claimed
US-7759417-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2010-07-20 US claimed
US-20090149581-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2009-06-11 US claimed
US-6855269-B2 Phenyl ether-substituted hydroxyphenyl triazine ultraviolet light absorbers CYTEC TECHNOLOGY CORP. (US) 2005-02-15 US claimed
US-6843939-B2 UV stabilizing additive composition CYTEC TECHNOLOGY CORP. (US) 2005-01-18 US claimed
US-20030146412-A1 Phenyl ether-substituted hydroxyphenyl triazine ultraviolet light absorbers CYTEC TECHNOLOGY CORP. 2003-08-07 US claimed
US-6509399-B2 Radiation resistance; absorber CYTEC TECHNOLOGY CORP 2003-01-21 US claimed
US-6384113-B1 POLYMER STABILIZER; LOW VOLATILITY; WEATHERABILITY; YELLOWING RESISTANCE CYTEC TECHNOLOGY CORP. 2002-05-07 US claimed
US-20020013462-A1 Non-yellowing part-tertiary-alkyl phenyl substituted triazine and pyrimidine ultraviolet light absorbers CYTEC INDUSTRIES CORP. 2002-01-31 US claimed
US-5081170-A Polyolefin, phenolic antioxidant, light stabilizer, sulfur antioxidant, talc filler, weatherproofing ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1992-01-14 US claimed
EP-4532595-A1 POLYCARBONATE COMPOSITION CONTAINING COMBINATION OF HYDROXYPHENYL TRIAZINES AND UV ABSORBERS BASF SE (DE) 2025-04-09 EP disclosed
EP-4341341-A1 STABILIZED POLYMER RESIN SYSTEMS HAVING HETEROPOLYOXOMETALATES FOR ANTIMICROBIAL PROPERTIES AND USES THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2024-03-27 EP disclosed
WO-2023227472-A1 POLYCARBONATE COMPOSITION CONTAINING COMBINATION OF HYDROXYPHENYL TRIAZINES AND UV ABSORBERS BASF SE (DE) 2023-11-30 WO disclosed
EP-4259711-A1 ADDITIVE MIXTURES BASF SE (DE) 2023-10-18 EP disclosed
US-7759417-B2 Stabilizer compositions CYTEC TECHNOLOGY CORP. (US) 2010-07-20 US disclosed
US-20090149581-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2009-06-11 US disclosed
US-6843939-B2 UV stabilizing additive composition CYTEC TECHNOLOGY CORP. (US) 2005-01-18 US disclosed
US-6545156-B1 Automobile overcoatings CYTEC TECHNOLOGY CORP. 2003-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030146412-A1 Phenyl ether-substituted hydroxyphenyl triazine ultraviolet light absorbers CRYZ, AHR, ERCC4 HMGCR 2712/4885GAA 2932/4885PKM 2673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.