Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952864 | 0.84 | NPC1 (0.33) | TSHRSMN1; SMN2CES2CES1TAS1R3 | |
| SCHEMBL16958945 | 0.84 | KDM4E (0.40) | TSHRPOLBALDH1A1 | |
| SCHEMBL16955646 | 0.82 | MEN1 (0.33) | — | |
| SCHEMBL16953467 | 0.82 | ALDH1A1 (0.32) | SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL16961310 | 0.81 | TSHR (0.36) | TSHRSMN1; SMN2CES2CES1TAS1R3 | |
| SCHEMBL16960328 | 0.81 | — | — | |
| SCHEMBL16960823 | 0.81 | PYCR1 (0.33) | PYCR1 | |
| SCHEMBL16952592 | 0.81 | CES2 (0.32) | CES2CES1 | |
| SCHEMBL16955699 | 0.79 | GABRA1 (0.38) | — | |
| SCHEMBL16962009 | 0.79 | CA2 (0.38) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |