SCHEMBL16952912

SCHEMBL16952912

[CH2]C(CO)c1ccc(Br)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 9/20 0.36
SLC6A4 P31645 1/20 0.35
CYP1A2 P05177 3/20 0.34
KDM1A O60341 2/20 0.33
KCNH2 Q12809 2/20 0.33
KDM1B Q8NB78 1/20 0.33
KIF11 P52732 1/20 0.32
SHBG P04278 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16956476 0.85 ADRB2 (0.36) ADRB2CYP1A2
SCHEMBL16957438 0.83 SLC6A4 (0.35) SLC6A4KDM1AKCNH2KDM1B
SCHEMBL16952104 0.82 CES2 (0.42) CYP1A2SHBG
SCHEMBL16958465 0.82
SCHEMBL28835620 0.79 KDM1A (0.35) SLC6A4CYP1A2KDM1AKCNH2KDM1B
SCHEMBL16956196 0.78 FFAR1 (0.37) SLC6A4CYP1A2KCNH2
SCHEMBL3611762 0.78 ADRB2 (0.40) ADRB2CYP1A2KDM1AKCNH2KDM1B
SCHEMBL16954367 0.78 ALDH1A1 (0.34) SLC6A4CYP1A2KCNH2
SCHEMBL3611759 0.78 ADRB2 (0.40) ADRB2CYP1A2KDM1AKCNH2KDM1B
SCHEMBL16955977 0.78 SHBG (0.31) SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed