Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858280 | 0.82 | CA12 (0.38) | GRM5 | |
| SCHEMBL9996940 | 0.82 | ALDH1A1 (0.40) | ACHE | |
| SCHEMBL26377782 | 0.76 | ACHE (0.36) | ACHERAPGEF4CHRNB2CHRNA4GRM5 | |
| SCHEMBL28896868 | 0.76 | ACHE (0.36) | ACHERAPGEF4CHRNB2CHRNA4GRM5 | |
| SCHEMBL255241 | 0.76 | GRM5 (0.45) | GRM5 | |
| SCHEMBL16959665 | 0.76 | ACHE (0.36) | ACHERAPGEF4CHRNB2CHRNA4GRM5 | |
| SCHEMBL16958514 | 0.73 | GABRA1 (0.34) | — | |
| SCHEMBL91512 | 0.73 | — | — | |
| SCHEMBL12156 | 0.73 | — | — | |
| SCHEMBL16961799 | 0.71 | RAPGEF4 (0.32) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |