Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226001 | 0.87 | ALDH1A1 (0.51) | BACE1CYP19A1ALDH1A1MAPK1TLR9 | |
| SCHEMBL1161468 | 0.85 | ALDH1A1 (0.60) | BACE1CYP19A1ALDH1A1MAPK1TLR9 | |
| SCHEMBL30766429 | 0.85 | ALDH1A1 (0.60) | BACE1CYP19A1ALDH1A1MAPK1TLR9 | |
| SCHEMBL16952061 | 0.83 | BACE1 (0.55) | BACE1CYP19A1ALDH1A1MAPK1TLR9 | |
| SCHEMBL16953824 | 0.83 | MAPT (0.61) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL6562723 | 0.81 | KMT2A (0.43) | BACE1ALDH1A1MAPK1TLR9MEN1 | |
| SCHEMBL14782201 | 0.81 | BACE1 (0.50) | BACE1CYP19A1ALDH1A1MAPK1TLR9 | |
| SCHEMBL16952303 | 0.80 | MEN1 (0.41) | BACE1CYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL14564249 | 0.80 | BACE1 (0.52) | BACE1CYP19A1ALDH1A1MAPK1TLR9 | |
| SCHEMBL8553361 | 0.79 | MAPT (0.45) | CYP19A1ALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165255-A1 | PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR | AFFERENT PHARMACEUTICALS INC. (US) | 2017-09-28 | — | — | WO | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |