Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452334 | 0.87 | MAPT (0.46) | KMT2AMEN1NPC1TLR9BACE1 | |
| SCHEMBL16953181 | 0.81 | BACE1 (0.52) | KMT2AMEN1NPC1TLR9BACE1 | |
| SCHEMBL823830 | 0.81 | ALDH1A1 (0.50) | KMT2AMEN1NPC1TLR9MAPT | |
| SCHEMBL18318758 | 0.79 | LMNA (0.47) | KMT2AMEN1MAPTPOLBACHE | |
| SCHEMBL1429398 | 0.78 | TSHR (0.54) | KMT2AMEN1NPC1TLR9MAPT | |
| SCHEMBL16295396 | 0.78 | KDM4E (0.54) | KMT2AMEN1NPC1TLR9BACE1 | |
| SCHEMBL9635580 | 0.78 | GPR35 (0.51) | KMT2AMEN1NPC1TLR9MAPT | |
| SCHEMBL28571803 | 0.78 | BACE1 (0.50) | KMT2AMEN1NPC1BACE1MAPT | |
| SCHEMBL16953824 | 0.78 | MAPT (0.61) | KMT2AMEN1NPC1MAPTPOLB | |
| SCHEMBL13779864 | 0.78 | MAPT (0.46) | KMT2AMEN1NPC1TLR9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996870-B1 | IMPROVED DISSOLUTION INHIBITION RESISTS FOR MICROLITHOGRAPHY | DU PONT (US) | 2004-03-24 | — | — | EP | disclosed |
| US-6319648-B1 | USED FOR IMAGING MATERIALS OF SEMICONDUCTOR DEVICE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-11-20 | — | — | US | disclosed |
| EP-0996870-A1 | IMPROVED DISSOLUTION INHIBITION RESISTS FOR MICROLITHOGRAPHY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999004319-A1 | IMPROVED DISSOLUTION INHIBITION RESISTS FOR MICROLITHOGRAPHY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-28 | — | — | WO | disclosed |