Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959072 | 0.90 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2C19CYP2D6MEN1 | |
| SCHEMBL16951429 | 0.87 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CYP2C19CYP2D6MEN1 | |
| SCHEMBL16956166 | 0.85 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP2C19CYP2D6MEN1 | |
| SCHEMBL3387371 | 0.82 | TSHR (0.49) | ALDH1A1CYP3A4CYP2C19TDP1HPGD | |
| SCHEMBL16958651 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4MEN1MAPTMAPK1 | |
| SCHEMBL16960922 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1MAPTMAPK1KMT2A | |
| SCHEMBL16954328 | 0.79 | GPR35 (0.50) | ALDH1A1CYP3A4MEN1MAPTMAPK1 | |
| SCHEMBL16955073 | 0.79 | THRB (0.35) | ALDH1A1CYP3A4CYP2C19CYP2D6MEN1 | |
| SCHEMBL16951682 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MEN1MAPTMAPK1KMT2A | |
| SCHEMBL16961133 | 0.78 | NPC1 (0.40) | ALDH1A1MEN1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |