Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958751 | 0.90 | ALDH1A1 (0.37) | ALDH1A1TDP1HPGDPOLBMEN1 | |
| SCHEMBL16950591 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TDP1HPGDPOLBMEN1 | |
| SCHEMBL16956166 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TDP1HPGDPOLBABCG2 | |
| SCHEMBL3387371 | 0.81 | TSHR (0.49) | ALDH1A1TDP1HPGDPOLBCYP3A4 | |
| SCHEMBL16951429 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TDP1HPGDPOLBABCG2 | |
| SCHEMBL16953702 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TDP1HPGDPOLBABCG2 | |
| SCHEMBL16951592 | 0.78 | GPR35 (0.50) | ALDH1A1TDP1HPGDPOLBMEN1 | |
| SCHEMBL16956299 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TDP1HPGDPOLBMEN1 | |
| SCHEMBL16956611 | 0.77 | HPD (0.39) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL16958739 | 0.77 | HPD (0.40) | ALDH1A1TDP1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |