Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.75 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.70 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.70 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.70 |
| ▸ | TYR | P14679 | 1/20 | 0.67 |
| ▸ | CTSL | P07711 | 3/20 | 0.66 |
| ▸ | CTSB | P07858 | 3/20 | 0.66 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | P4HB | P07237 | 1/20 | 0.65 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | F3 | P13726 | 1/20 | 0.65 |
| ▸ | XDH | P47989 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.62 |
| ▸ | DPP4 | P27487 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603827 | 1.00 | CHRNA7 (0.75) | CHRNA7GABRA3GABRA2GABRB2TYR | |
| SCHEMBL28339980 | 0.94 | GABRA3 (0.78) | CHRNA7GABRA3GABRA2GABRB2CTSL | |
| SCHEMBL4139154 | 0.94 | GABRA3 (0.78) | CHRNA7GABRA3GABRA2GABRB2CTSL | |
| SCHEMBL10384464 | 0.89 | GABRA3 (0.84) | GABRA3GABRA2GABRB2CTSLCTSB | |
| SCHEMBL26113846 | 0.87 | CTSB (0.86) | CHRNA7GABRA3GABRA2GABRB2CTSL | |
| SCHEMBL1695380 | 0.86 | CHRNA7 (1.00) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL21446884 | 0.86 | CHRNA7 (1.00) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL1695381 | 0.86 | CHRNA7 (1.00) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL28906370 | 0.86 | CTSL (0.63) | CHRNA7GABRA3GABRA2GABRB2CTSL | |
| SCHEMBL7656528 | 0.86 | MAPT (0.76) | CHRNA7GABRA3GABRA2GABRB2TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242144-B2 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-08-14 | — | — | US | disclosed |
| US-20110082176-A1 | Stilbenes and Chalcones for the Prevention and Treatment of Cardiovascular Diseases | RESVERLOGIX CORP. | 2011-04-07 | — | — | US | disclosed |
| US-7846915-B2 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | Resverlogix Corporation (CA) | 2010-12-07 | — | — | US | disclosed |
| US-20060205792-A1 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | HEPALINK (HONG KONG) LIMITED (HK) | 2006-09-14 | — | — | US | disclosed |
| WO-2006045010-A2 | STILBENES AND CHALCONES FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. (CA) | 2006-04-27 | — | — | WO | disclosed |
| US-4867964-A | SUNSCREEN | L'OREAL (FR) | 1989-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205792-A1 | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases | APOB, APOL1, HDLBP | CHRNA7 3919/4885GABRA3 4781/4885GABRA2 4804/4885 |
| US-20110082176-A1 | Stilbenes and Chalcones for the Prevention and Treatment of Cardiovascular Diseases | APOB, APOL1, HDLBP | CHRNA7 3919/4885GABRA3 4781/4885GABRA2 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.