Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959030 | 0.83 | NFE2L2 (0.34) | ERN1NFE2L2 | |
| SCHEMBL28949165 | 0.83 | ERN1 (0.48) | ERN1NFE2L2HCRTR1HCRTR2 | |
| SCHEMBL29980534 | 0.83 | ERN1 (0.48) | ERN1NFE2L2HCRTR1HCRTR2 | |
| SCHEMBL8727533 | 0.81 | EPAS1 (0.34) | HCRTR1HCRTR2TRPV1SCN8ASCN10A | |
| SCHEMBL16959166 | 0.81 | CA2 (0.42) | ERN1 | |
| SCHEMBL16951128 | 0.81 | GAA (0.36) | NFE2L2GRIN1GRIN2B | |
| SCHEMBL16955869 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL16957157 | 0.79 | TRPV1 (0.35) | TRPV1 | |
| SCHEMBL16955011 | 0.79 | SCN8A (0.38) | SCN8ASCN10A | |
| SCHEMBL16957089 | 0.79 | HSD11B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |