Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955225 | 0.90 | CYP1A1 (0.47) | ALDH1A1MAPTCYP1A1CYP1B1 | |
| SCHEMBL16959527 | 0.88 | GPR3 (0.34) | GPR3PIM1PIM2 | |
| SCHEMBL21945554 | 0.88 | AURKA (0.37) | GPR3PIM1PIM2ALDH1A1MAPT | |
| SCHEMBL16953532 | 0.86 | GPR3 (0.31) | GPR3PIM1PIM2 | |
| SCHEMBL16960184 | 0.86 | NOTUM (0.42) | GPR3PIM1PIM2EPHX2 | |
| SCHEMBL16956540 | 0.86 | PGR (0.33) | GPR3PIM1PIM2ALDH1A1 | |
| SCHEMBL18002803 | 0.86 | PIM1 (0.33) | GPR3PIM1PIM2EPHX2 | |
| SCHEMBL16956507 | 0.86 | FFAR4 (0.37) | — | |
| SCHEMBL16950777 | 0.86 | PGR (0.37) | — | |
| SCHEMBL16961415 | 0.86 | L3MBTL1 (0.40) | ALDH1A1CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |