SCHEMBL16956540

SCHEMBL16956540

C=Cc1cc(Br)cc(OC(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.33
GPR3 P46089 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
PIM1 P11309 1/20 0.30
PIM2 Q9P1W9 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16954166 0.86 GPR3 (0.35) GPR3PIM1PIM2ALDH1A1
SCHEMBL29417674 0.81 ALDH1A1 (0.38) PGRGPR3CA1CA2CA7
SCHEMBL12075823 0.81 ALDH1A1 (0.38) PGRGPR3CA1CA2CA7
SCHEMBL16959488 0.81 PGR (0.33) PGRGPR3CA1CA2CA7
SCHEMBL1510479 0.80 PGR (0.39) PGRGPR3CA1CA2CA7
SCHEMBL12160006 0.80 PGR (0.39) PGRGPR3CA1CA2CA7
SCHEMBL16959527 0.79 GPR3 (0.34) GPR3PIM1PIM2
SCHEMBL21945554 0.79 AURKA (0.37) GPR3PIM1PIM2ALDH1A1
SCHEMBL18002803 0.78 PIM1 (0.33) GPR3PIM1PIM2
SCHEMBL16953532 0.78 GPR3 (0.31) GPR3PIM1PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed