Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199588 | 0.85 | JAK2 (0.57) | JAK2JAK1TYK2PDE2AGAA | |
| SCHEMBL30740081 | 0.85 | JAK2 (0.57) | JAK2JAK1TYK2PDE2AGAA | |
| SCHEMBL14533723 | 0.85 | JAK2 (0.47) | JAK2JAK1TYK2PDE2AGAA | |
| SCHEMBL16959559 | 0.82 | PDE2A (0.47) | JAK2JAK1TYK2PDE2AGAA | |
| SCHEMBL16950454 | 0.80 | JAK2 (0.43) | JAK2JAK1TYK2PDE2AGAA | |
| SCHEMBL10658142 | 0.80 | JAK2 (0.56) | JAK2JAK1TYK2PDE2ACES2 | |
| SCHEMBL78221 | 0.78 | MRGPRX4 (0.61) | JAK2JAK1TYK2CES2ALDH1A1 | |
| SCHEMBL477732 | 0.78 | JAK2 (0.55) | JAK2JAK1TYK2PDE2ACES2 | |
| SCHEMBL629096 | 0.77 | CASP1 (0.55) | JAK2JAK1TYK2CES2TSHR | |
| Hydrochloric Acid SCHEMBL18861026 | 0.77 | MRGPRX4 (0.59) | JAK2JAK1TYK2CES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |