Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954266 | 0.82 | JAK2 (0.49) | PDE2AJAK2JAK1TYK2MRGPRX4 | |
| SCHEMBL16950504 | 0.81 | CES2 (0.41) | PDE2AGAACYP2D6CES2HPGD | |
| SCHEMBL16961328 | 0.79 | CES2 (0.40) | PDE2AGAACYP2D6CES2HPGD | |
| SCHEMBL14533723 | 0.79 | JAK2 (0.47) | PDE2AJAK2JAK1TYK2MRGPRX4 | |
| SCHEMBL30740081 | 0.79 | JAK2 (0.57) | PDE2AJAK2JAK1TYK2MRGPRX4 | |
| SCHEMBL1199588 | 0.79 | JAK2 (0.57) | PDE2AJAK2JAK1TYK2MRGPRX4 | |
| SCHEMBL16957261 | 0.78 | CES2 (0.42) | PDE2AJAK2JAK1TYK2MRGPRX4 | |
| SCHEMBL16960076 | 0.77 | CES2 (0.35) | CES2HTR2ASLC6A4KCNH2HPGD | |
| SCHEMBL16954719 | 0.76 | ALDH1A1 (0.50) | JAK2JAK1TYK2HTTTSHR | |
| SCHEMBL16956711 | 0.76 | AR (0.44) | PDE2ACYP2D6CES2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |