SCHEMBL16954292

SCHEMBL16954292

C=[C]c1cc(OC)ccc1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
ALDH1A1 P00352 3/20 0.48
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
THRB P10828 1/20 0.48
CYP1A1 P04798 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP1B1 Q16678 2/20 0.44
CYP3A4 P08684 1/20 0.44
IDO1 P14902 2/20 0.43
ADRA1A P35348 2/20 0.43
NFE2L2 Q16236 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16960955 0.83 NQO1 (0.43) ALDH1A1MAPTKMT2AHTTNPSR1
SCHEMBL16955603 0.83 CA1 (0.42) CA12CA1CA2CA7CA9
SCHEMBL16961539 0.83 CALM1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL16950905 0.82 MAPT (0.41) CA12CA1CA2CA7CA9
SCHEMBL16956034 0.82 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL16959106 0.82 GPR3 (0.39) CA12CA1CA2CA7CA9
SCHEMBL9177034 0.81 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL16952923 0.79 ACHE (0.56) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL16955428 0.79 CA12 (0.40) CA12CA1CA2CA7CA9
SCHEMBL9996389 0.79 CA12 (0.56) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed