Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029109 | 0.79 | ALDH1A1 (0.63) | ACHEALDH1A1CYP3A4USP2KDM4E | |
| SCHEMBL16954292 | 0.79 | CA12 (0.56) | ALDH1A1CYP3A4USP2KMT2AMAPT | |
| SCHEMBL19757165 | 0.79 | ACHE (0.56) | ACHEALDH1A1CYP3A4USP2KDM4E | |
| SCHEMBL16958264 | 0.79 | MAPT (0.44) | ACHEALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL16957433 | 0.79 | ACHE (0.36) | ACHEALDH1A1CYP3A4USP2MAPT | |
| SCHEMBL16952060 | 0.78 | KDM4E (0.39) | ALDH1A1USP2KDM4EKMT2AMAPT | |
| SCHEMBL16957005 | 0.78 | PTGDR2 (0.44) | ALDH1A1USP2KDM4EKMT2AL3MBTL1 | |
| SCHEMBL16954046 | 0.78 | NFE2L2 (0.42) | ALDH1A1USP2KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL16952374 | 0.77 | GPR3 (0.38) | ACHEALDH1A1CYP3A4AR | |
| SCHEMBL16951886 | 0.77 | ALDH1A1 (0.44) | ACHEALDH1A1CYP3A4KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |